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Conquer Your Internal Medicine Daily Quiz

Sharpen Diagnostic Skills with Daily Quiz Cases

Difficulty: Moderate
Questions: 20
Learning OutcomesStudy Material
Colorful paper art depicting elements related to Internal Medicine Daily Quiz.

Looking to sharpen your clinical reasoning every day? The Internal Medicine Daily Quiz offers 15 targeted MCQs made for students and busy clinicians who want a quick brain workout. Those preparing for board exams or seeking to review core concepts will find practical value in each case. Feel free to compare results with our Internal Medicine MCQ Quiz or explore the Internal Medicine Clinical Knowledge Quiz for more challenges. You can also customize any quiz freely in our editor and browse additional quizzes to fit your study goals.

Which fasting plasma glucose level is diagnostic of diabetes mellitus?
126 mg/dL
110 mg/dL
140 mg/dL
100 mg/dL
A fasting plasma glucose level of 126 mg/dL or higher on at least two occasions is diagnostic of diabetes mellitus. Lower levels do not meet the diagnostic criteria.
Which condition most commonly causes microcytic hypochromic anemia in adults?
Vitamin B12 deficiency
Beta-thalassemia minor
Sickle cell anemia
Iron deficiency anemia
Iron deficiency is the most common cause of microcytic hypochromic anemia in adults. Other causes like thalassemias are less common in the general population.
What is the most common bacterial cause of community-acquired pneumonia?
Mycoplasma pneumoniae
Streptococcus pneumoniae
Staphylococcus aureus
Haemophilus influenzae
Streptococcus pneumoniae is the leading cause of community-acquired pneumonia. Other pathogens are possible but less frequent.
Hypertension is defined as a blood pressure reading of at least which of the following?
150/95 mm Hg
130/80 mm Hg
140/90 mm Hg
120/80 mm Hg
Hypertension is defined by a systolic blood pressure ≥140 mm Hg or a diastolic blood pressure ≥90 mm Hg. Lower readings are considered prehypertension or normal.
Which vitamin deficiency leads to macrocytic anemia and neurologic symptoms?
Folate
Vitamin D
Vitamin C
Vitamin B12
Vitamin B12 deficiency causes macrocytic anemia and can lead to neurologic symptoms due to demyelination. Folate deficiency causes macrocytic anemia but lacks neurologic findings.
ST-segment elevations in leads V1 through V4 most likely indicate occlusion of which coronary artery?
Left circumflex artery
Posterior descending artery
Right coronary artery
Left anterior descending artery
ST elevations in V1 - V4 represent anteroseptal myocardial infarction, most commonly due to occlusion of the left anterior descending artery.
A euvolemic patient with hyponatremia, low serum osmolality, and high urine osmolality is most consistent with which diagnosis?
Dehydration
Diabetes insipidus
Primary hyperaldosteronism
Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
SIADH causes euvolemic hyponatremia with low serum osmolality and inappropriately concentrated urine (high urine osmolality).
What is the first-line treatment for a symptomatic bradycardia with hypotension?
Intravenous metoprolol
Intravenous atropine
Intravenous epinephrine
Intravenous adenosine
Atropine is the first-line agent to increase heart rate in symptomatic bradycardia. Epinephrine is reserved if atropine is ineffective.
A patient presents with sharp chest pain relieved by leaning forward and a pericardial friction rub. What is the initial management?
Nonsteroidal anti-inflammatory drugs
Immediate pericardiocentesis
Intravenous beta blockers
High-dose corticosteroids
Acute pericarditis is initially treated with NSAIDs to reduce inflammation. Steroids are reserved for refractory cases.
In a patient on warfarin with an INR of 10 and no bleeding, what is the most appropriate management?
Continue warfarin at the same dose
Switch to low molecular weight heparin
Hold warfarin and give oral vitamin K
Administer fresh frozen plasma
For an INR >10 without bleeding, warfarin should be held and low-dose oral vitamin K administered to reduce bleeding risk.
High-resolution CT of a patient shows subpleural reticulation and honeycombing. Which diagnosis is most likely?
Asbestosis
Pulmonary edema
Idiopathic pulmonary fibrosis
Sarcoidosis
The CT pattern of subpleural reticulation and honeycombing is classic for idiopathic pulmonary fibrosis. Other diseases have different imaging features.
What is the best initial imaging test for a hemodynamically stable patient with suspected pulmonary embolism?
CT pulmonary angiography
Lower extremity Doppler ultrasound
Ventilation-perfusion scan
Chest radiograph
CT pulmonary angiography is the preferred initial study in stable patients to directly visualize pulmonary arteries and detect emboli.
Which procedure is essential for diagnosing spontaneous bacterial peritonitis in a cirrhotic patient with ascites?
Upper endoscopy
Diagnostic paracentesis
Liver biopsy
Abdominal CT scan
Diagnostic paracentesis with ascitic fluid analysis is required to confirm spontaneous bacterial peritonitis by cell count and culture.
A patient develops a 50% drop in platelets 7 days after starting heparin. Which is the most appropriate next step?
Stop heparin and start argatroban
Begin low-dose aspirin
Increase heparin dose
Continue heparin with platelet monitoring
Heparin-induced thrombocytopenia requires immediate discontinuation of heparin and initiation of a direct thrombin inhibitor such as argatroban.
Which treatment stabilizes the cardiac membrane in hyperkalemia with ECG changes?
IV insulin with glucose
Oral potassium
IV calcium gluconate
Loop diuretics
IV calcium gluconate stabilizes the cardiac myocyte membrane and reduces the risk of arrhythmias in hyperkalemia presenting with ECG changes.
Which screening test is most appropriate for a patient suspected of having primary hyperaldosteronism?
Dexamethasone suppression test
24-hour urinary catecholamines
Serum cortisol level
Plasma aldosterone-renin ratio
An elevated plasma aldosterone-renin ratio is the recommended screening test for primary hyperaldosteronism due to autonomous aldosterone secretion.
What is the first-line vasopressor for treating septic shock in adults?
Phenylephrine
Dopamine
Epinephrine
Norepinephrine
Norepinephrine is the recommended first-line vasopressor in septic shock to maintain mean arterial pressure and organ perfusion.
Which of the following is the treatment of choice for torsades de pointes?
IV magnesium sulfate
Immediate electrical cardioversion
IV potassium chloride
IV amiodarone
IV magnesium sulfate is the treatment of choice for torsades de pointes, even if magnesium levels are normal, as it stabilizes the myocardium.
In a patient with cardiogenic shock following acute MI, which intervention can increase coronary perfusion and decrease afterload?
IV nitroprusside
Continuous heparin infusion
External pacemaker
Intra-aortic balloon pump
An intra-aortic balloon pump inflates during diastole to augment coronary perfusion and deflates during systole to reduce afterload in cardiogenic shock.
A patient with hemoptysis and rapidly progressive glomerulonephritis tests positive for anti-glomerular basement membrane antibodies. What is the most appropriate initial treatment?
High-dose methotrexate
Intravenous heparin
Oral prednisone alone
Plasmapheresis
Goodpasture syndrome is treated urgently with plasmapheresis to remove pathogenic antibodies, along with immunosuppression. Prednisone alone is insufficient initially.
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Learning Outcomes

  1. Analyze patient presentations for accurate diagnoses.
  2. Evaluate clinical data to determine effective treatment plans.
  3. Identify key signs and symptoms of internal diseases.
  4. Apply evidence-based guidelines in managing common conditions.
  5. Demonstrate critical decision-making in acute care scenarios.
  6. Master differential diagnosis processes for complex cases.

Cheat Sheet

  1. Master Patient History-Taking & Physical Examination - Think of yourself as a detective: each question and every physical finding fills in another piece of the mystery. Sharpen these foundational skills to build comprehensive clinical data, ensuring you catch subtle clues others might miss. DeGowin's Diagnostic Examination
  2. Conquer Biostatistics with Sensitivity & Specificity - Turn daunting numbers into powerful diagnostic tools by mastering "SPin" and "SNout" mnemonics. Understanding how to rule tests in or out accurately will boost your confidence when interpreting lab results. 5 General Internal Medicine Concepts to Master
  3. Apply the Centor Criteria for Sore Throats - Fever, no cough, tender front-neck lymph nodes, and tonsil exudates: these four clues can predict strep like a seasoned pro. Use this quick assessment to decide when antibiotics may be needed. 5 General Internal Medicine Concepts to Master
  4. Stay Current on Evidence-Based Guidelines - Hypertension, diabetes, and heart failure evolve faster than your favorite TV series plot twists. Regularly reviewing the latest guidelines ensures you're giving patients top-notch, up-to-date care. Mayo Clinic Internal Medicine Resources
  5. Hone Acute Care Decision-Making - In high-pressure scenarios, quick yet informed choices can save lives. Engage with case studies and simulations that sharpen your reflexes and reinforce critical thinking. Internal Medicine Case Reviews and Study Guides
  6. Perfect the Differential Diagnosis Process - Systematically brainstorm every possible cause before zeroing in on one - think of it as mental gymnastics for your diagnostic brain. This methodical approach leads to more accurate and confident conclusions. Case Files Internal Medicine
  7. Champion Smoking Cessation Strategies - Motivating patients to quit is part science, part art - and sometimes aided by medications like varenicline or bupropion. Know the benefits, watch for contraindications, and support each step toward a smoke-free life. 5 General Internal Medicine Concepts to Master
  8. Screen with the CAGE Questionnaire - Just four simple questions can uncover alcohol use disorders in a flash. A score of two or more means it's time to dig deeper and offer support. 5 General Internal Medicine Concepts to Master
  9. Explore Core Internal Medicine Principles - Dive into a comprehensive roadmap that takes you through the heart of internal medicine, from pathophysiology to practical patient care pearls. Staying informed here lays the groundwork for your entire clinical journey. Understanding Internal Medicine: A Guide for Medical Students
  10. Engage with Interactive Clinical Learning Tools - Hands-on simulations and interactive modules are like video games for med students - engaging, fun, and packed with real-world skills. Boost your retention and application of key concepts in a low-stakes environment. UC San Diego's Practical Guide to Clinical Medicine
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