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Quizzes > Quizzes for Business > Healthcare

Take the HIV Knowledge Assessment Quiz

Boost HIV awareness with interactive questions

Difficulty: Moderate
Questions: 20
Learning OutcomesStudy Material
Colorful paper art illustrating a fun HIV Knowledge Assessment Quiz

Ready to challenge your understanding of HIV prevention and treatment? This HIV knowledge assessment quiz features 15 multiple-choice questions on transmission, care, and risk factors to sharpen comprehension and boost confidence. Ideal for students, educators, and healthcare professionals, it can be freely modified in our editor to fit any learning objective. Compare your skills with similar tools like the HIV Self-Testing Knowledge Quiz or the Knowledge Assessment Quiz , and explore more quizzes for ongoing practice.

Which of the following is the primary bodily fluid through which HIV is transmitted?
Sweat
Saliva
Blood
Urine
HIV is primarily transmitted through blood due to the high viral concentration. Other fluids like saliva, sweat, and urine contain insufficient virus particles to cause transmission under normal circumstances.
Which practice is most effective in reducing sexual transmission of HIV?
Consistent use of latex condoms
Doubling up condoms
Taking birth control pills
Using the withdrawal method
Latex condoms provide a barrier that prevents exchange of infected bodily fluids during sexual activity. Methods like withdrawal or hormonal birth control do not protect against HIV, and doubling condoms can increase risk of breakage.
During which stage of HIV infection is the viral load highest?
Seroconversion window period
Acute infection
AIDS
Clinical latency
The acute infection stage is marked by rapid viral replication and the highest viral load. Clinical latency has lower steady replication, and AIDS may vary depending on treatment status.
Which of the following is NOT a recognized mode of HIV transmission?
Sharing needles
Unprotected sex
Transmission from mother to child during childbirth
Kissing with no blood exchange
HIV cannot be transmitted through closed-mouth kissing unless there is blood present. Sharing needles, unprotected sexual contact, and mother-to-child transmission are established routes.
What does the term "seroconversion" refer to in HIV infection?
Development of detectable antibodies against HIV
Complete elimination of the virus
Initial viral entry into cells
Progression to AIDS
Seroconversion is the period when specific antibodies to HIV become detectable in the blood. It does not indicate viral eradication or signify progression to AIDS.
Which HIV prevention strategy should be initiated within 72 hours after a high-risk exposure?
Antiretroviral therapy (ART)
Pre-exposure prophylaxis (PrEP)
Post-exposure prophylaxis (PEP)
Condom use
PEP is specifically designed to be taken as soon as possible - and within 72 hours - after a potential HIV exposure. PrEP is taken before potential exposures, while ART and condoms are not immediate post-exposure interventions.
Co-infection with which sexually transmitted infection most significantly increases HIV transmission risk?
Chlamydia
Human papillomavirus (HPV)
Genital herpes
Bacterial vaginosis
Genital herpes causes mucosal ulcerations that facilitate both entry and exit of HIV, significantly raising transmission risk. While other STIs cause inflammation, their direct impact on HIV transmission is lower.
What is the HIV "window period"?
The time between acute infection and AIDS
The period of clinical latency
The time between infection and detectable antibodies
The time after seroconversion
The window period refers to the interval from initial HIV infection until antibodies become detectable by standard tests. It does not describe the latency phase or progression to later stages.
Which laboratory test is most commonly used to monitor immune system health in HIV-infected individuals?
HIV antibody ELISA
Serum creatinine levels
Viral culture
CD4+ T-cell count
CD4+ T-cell counts reflect the functional status of the immune system and guide treatment decisions. Viral cultures are not routinely used, creatinine measures kidney function, and ELISA tests detect antibodies rather than immune competence.
Nucleoside reverse transcriptase inhibitors (NRTIs) act by:
Preventing viral fusion
Blocking HIV protease
Inhibiting integrase
Incorporating into viral DNA to cause chain termination
NRTIs mimic natural nucleosides and get incorporated into the growing viral DNA strand, leading to premature chain termination. Other classes of drugs target protease, fusion, or integrase functions.
Why is strict adherence to antiretroviral therapy critical?
To eliminate the need for CD4 monitoring
To immediately increase white blood cell count
To prevent development of resistant HIV strains
To enhance vaccine responses
Consistent medication adherence maintains therapeutic drug levels that suppress viral replication and prevent resistance. Poor adherence can lead to viral rebound and resistant strains.
Which behavior poses the highest risk of HIV transmission among injecting drug users?
Using communal rinse water
Cleaning needles with water
Disposing needles in sharps containers
Sharing needles and syringes
Direct sharing of contaminated needles transfers infected blood between users and poses the highest risk. Proper cleaning and disposal practices reduce transmission risk.
Which group is most appropriate for pre-exposure prophylaxis (PrEP)?
HIV-negative individuals at ongoing high risk
HIV-positive individuals starting therapy
Pregnant women with HIV
Individuals who have recovered from HIV
PrEP is indicated for HIV-negative persons who face regular exposure risk, helping to prevent infection. It is not used by HIV-positive individuals or those already infected.
Maternal viral load reduction during pregnancy is most effectively achieved by:
Administering antiretroviral therapy to the mother
Performing cesarean section delivery alone
Providing vitamins to the newborn
Advising exclusive formula feeding without ART
Maternal ART suppresses viral replication, significantly reducing the risk of mother-to-child transmission. Delivery mode and feeding practices are supportive measures but secondary to viral suppression.
During the clinical latency stage of HIV infection:
The patient experiences severe opportunistic infections
Viral load peaks dramatically
The virus replicates at low levels and the patient may be asymptomatic
HIV antibodies are undetectable
Clinical latency is characterized by slow, persistent viral replication and often no symptoms. Severe infections, peak viral loads, and undetectable antibodies occur in other stages.
Which host cell co-receptor is most commonly used by HIV-1 during early infection?
CCR5
CXCR4
CD8
gp41
HIV-1 typically uses the CCR5 co-receptor on CD4+ T cells during initial infection. CXCR4-tropic variants often appear later, while CD8 and gp41 are not entry co-receptors.
Maraviroc, a CCR5 antagonist, exerts its antiviral effect by:
Preventing protease activity
Blocking HIV binding to CCR5 on host cells
Inhibiting reverse transcriptase
Interfering with gp41 fusion
Maraviroc binds to and blocks the CCR5 receptor, preventing HIV-1 from attaching and entering the host cell. It does not target reverse transcriptase, protease, or the fusion peptide directly.
Which statement best describes the U=U (Undetectable = Untransmittable) concept?
Undetectable viral load means the virus is eradicated from the body
Undetectable status is achieved without medication
People with sustained undetectable viral load cannot sexually transmit HIV
All transmission routes are blocked at undetectable levels
Clinical evidence shows that sustained undetectable viral load through effective ART prevents sexual HIV transmission. The virus remains in reservoirs, and maintaining undetectable status requires ongoing therapy.
In patients on ART, a rebound in viral load is most likely due to:
Elevated CD4+ count
Initial infection with CCR5-tropic virus
Seroconversion during acute infection
Poor adherence leading to drug resistance
Missed doses or irregular adherence allow HIV replication to resume and select for resistant strains, causing viral rebound. Tropism, CD4 counts, and seroconversion do not explain a rebound after suppression.
Which immunological marker is most predictive of progression from HIV infection to AIDS?
Increase in CD8+ T-cell count above 1000 cells/mm3
Reduction in viral load to undetectable levels
Elevated total IgG antibody levels
Decline in CD4+ T-cell count below 200 cells/mm3
A CD4+ T-cell count falling below 200 cells/mm3 is the clinical threshold defining progression to AIDS. Other markers like CD8 counts or antibody levels are not used for this classification.
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Learning Outcomes

  1. Identify modes of HIV transmission and prevention strategies
  2. Analyse stages of HIV infection and immune response
  3. Evaluate risk factors related to HIV exposure
  4. Demonstrate knowledge of treatment and care options
  5. Apply safe practices to reduce HIV transmission

Cheat Sheet

  1. Primary Modes of Transmission - HIV can be spread through unprotected anal or vaginal sex, sharing contaminated needles, and from mother to child during birth or breastfeeding. Understanding these routes empowers you to make safer choices and reduce risk in everyday life. CDC HIV Prevention
  2. Stages of HIV Infection - HIV progresses through three key phases: acute infection, chronic infection, and AIDS. Knowing these stages helps you recognize symptoms, understand your viral load, and stay informed about treatment timing. NIH HIV Stages Fact Sheet
  3. Importance of Early ART - Starting antiretroviral therapy (ART) as soon as possible can slow disease progression, boost immune health, and improve long-term outcomes. Early treatment also reduces the amount of virus in the blood, lowering transmission risk to others. NIH HIV Stages Fact Sheet
  4. STIs and Increased HIV Risk - Having another sexually transmitted infection can cause inflammation and breaks in the skin or mucous membranes, making it easier for HIV to enter the body. Regular STI screenings and prompt treatment can help you maintain your sexual health. HIV Prevention Basics - NIH
  5. Condom Effectiveness - When used consistently and correctly, condoms provide a powerful barrier against HIV and many other STIs. Keep a supply handy and communicate openly with partners about safer sex practices. CDC HIV Prevention
  6. Pre-Exposure Prophylaxis (PrEP) - PrEP is a daily pill that, when taken as prescribed, can reduce your risk of HIV infection by over 90% in high-risk individuals. Talk to a healthcare provider about whether PrEP is right for you. HIV Prevention Basics - NIH
  7. Post-Exposure Prophylaxis (PEP) - PEP involves taking HIV medications within 72 hours after potential exposure to prevent the virus from taking hold. It's a short-term measure that must be started quickly, so know where to access PEP services. CDC HIV Prevention
  8. Undetectable = Untransmittable - People living with HIV who take ART and achieve an undetectable viral load have virtually no risk of transmitting the virus to sexual partners. This fact underscores the power of consistent treatment. HIV.gov U=U Information
  9. Needle Sharing Risks - Sharing needles or syringes for drug use is one of the highest-risk activities for HIV transmission. Seek out needle exchange programs and use sterile equipment every time to stay safe. CDC HIV Prevention
  10. Regular HIV Testing - Knowing your HIV status through routine testing is a crucial step in prevention, early detection, and timely treatment if needed. Make testing a regular habit - knowledge is power! Stop HIV Together - CDC
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