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Quizzes > Health & Medicine > Diseases & Conditions

Test Your Psoriatic Arthritis Knowledge Now!

Dive into our psoriatic arthritis symptoms quiz - can you ace every question?

Difficulty: Moderate
2-5mins
Learning OutcomesCheat Sheet
Paper art joints rash icons on teal background for psoriatic arthritis quiz

Think you know psoriatic arthritis inside out? Our free Psoriatic Arthritis Quiz is here to put your expertise to the test and deepen your understanding of this complex condition. You'll tackle psoriatic arthritis questions on symptoms, triggers, and treatments, and explore engaging psoriatic arthritis trivia designed to challenge both newcomers and long-time advocates. Whether you want to brush up on early signs with our psoriatic arthritis symptoms quiz or simply test your psoriatic arthritis knowledge, this is your chance to learn something new. Jump in now with this psoriatic arthritis quiz - and why not see how you fare against a broader arthritis quiz? Ready, set, go!

Psoriatic arthritis is best classified as which type of arthritis?
Infectious arthritis
Inflammatory arthritis
Metabolic arthritis
Degenerative arthritis
Psoriatic arthritis is a chronic inflammatory arthritis associated with psoriasis and is characterized by joint inflammation without infection. It falls under the category of spondyloarthropathies. Management often includes anti-inflammatory and immunosuppressive therapies. Mayo Clinic
Which skin condition is most commonly associated with psoriatic arthritis?
Vitiligo
Eczema
Seborrheic dermatitis
Psoriasis
Psoriasis, a chronic autoimmune skin disease characterized by scaly plaques, most commonly precedes or accompanies psoriatic arthritis. Up to 30% of patients with psoriasis develop joint involvement. The temporal relationship can vary, with joints affected before, during, or after skin lesions. NIAMS
Which joint pattern is considered most characteristic of psoriatic arthritis?
Sacroiliac joint involvement only
Proximal interphalangeal joint involvement
Distal interphalangeal joint involvement
Metacarpophalangeal joint involvement
Psoriatic arthritis often affects the distal interphalangeal (DIP) joints of fingers and toes, which is uncommon in rheumatoid arthritis. DIP involvement, along with nail changes and dactylitis, helps distinguish psoriatic arthritis. Radiographs may show both erosions and new bone formation at these sites. American College of Rheumatology
Which nail abnormality is frequently observed in patients with psoriatic arthritis?
Pitting
Leukonychia
Koilonychia
Beau's lines
Nail pitting - small depressions on the nail surface - is a common finding in psoriatic arthritis and psoriasis. It reflects involvement of the nail matrix by psoriatic inflammation. Nail changes may precede joint symptoms and aid early diagnosis. Mayo Clinic
Which age group is most commonly affected by psoriatic arthritis?
Children under 10 years
Adolescents aged 10 - 19 years
Adults older than 70 years
Adults aged 30 - 50 years
Psoriatic arthritis most frequently begins in adults between 30 and 50 years of age, although it can occur at any age. Childhood onset is less common and may present differently. Early recognition in this age group can prevent joint damage. NIAMS
Which HLA allele is most strongly associated with psoriatic arthritis susceptibility?
HLA-DR3
HLA-B27
HLA-DR4
HLA-A3
HLA-B27 is strongly linked to the spondyloarthropathy spectrum, including psoriatic arthritis, especially when axial involvement is present. Its presence correlates with more severe spinal disease. Genetic screening may support diagnosis in ambiguous cases. American College of Rheumatology
Which imaging modality is most commonly used to detect both erosive changes and new bone formation in psoriatic arthritis?
Computed tomography (CT)
Magnetic resonance imaging (MRI)
Ultrasound
Plain radiography (X-ray)
Plain radiographs are the first-line imaging for suspected psoriatic arthritis due to their ability to show characteristic erosions and bone proliferation. MRI and ultrasound have higher sensitivity but are used when radiographs are inconclusive. Radiographic patterns help guide management. NCBI
What term describes the diffuse swelling of an entire finger or toe seen in psoriatic arthritis?
Bursitis
Enthesitis
Dactylitis
Tenosynovitis
Dactylitis, or 'sausage digit,' refers to uniform swelling of an entire finger or toe and is a hallmark feature of psoriatic arthritis. It results from combined synovitis, tenosynovitis, and soft tissue inflammation. Early recognition aids diagnosis and treatment. NIAMS
Which class of medication is considered first-line for symptomatic relief in mild to moderate psoriatic arthritis?
Corticosteroid injections
NSAIDs
Antimalarials
Biologic DMARDs
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the first-line therapy for mild to moderate psoriatic arthritis, providing symptomatic relief of pain and stiffness. Disease-modifying agents are added if there is poor control or radiographic progression. American College of Rheumatology
Which laboratory test is usually negative in psoriatic arthritis?
C-reactive protein
HLA-B27
Rheumatoid factor
Erythrocyte sedimentation rate
Psoriatic arthritis is typically seronegative, meaning the rheumatoid factor is usually negative. Elevated ESR and CRP reflect active inflammation but are not specific. HLA-B27 can be positive in a subset with axial disease. Mayo Clinic
Which subtype of psoriatic arthritis is characterized predominantly by distal interphalangeal joint involvement?
Oligoarthritis
Symmetric polyarthritis
Distal interphalangeal predominant
Spondylitis
Moll and Wright characterized psoriatic arthritis into subtypes including the distal interphalangeal predominant form, where DIP joints are chiefly involved. Identifying the subtype guides prognosis and therapy. NCBI
Enthesitis in psoriatic arthritis refers to inflammation of which structure?
Bursa adjacent to the joint
Synovial lining of the joint
Insertion of tendon or ligament into bone
Cartilage surface
Enthesitis is inflammation at the enthesis, where tendons or ligaments attach to bone, and is a hallmark of spondyloarthropathies including psoriatic arthritis. Common sites include the Achilles tendon and plantar fascia. Early detection prevents structural damage. American College of Rheumatology
Which biologic agent specifically targets the cytokine IL-17A in the treatment of psoriatic arthritis?
Secukinumab
Etanercept
Rituximab
Ustekinumab
Secukinumab is a monoclonal antibody that neutralizes IL-17A, a key cytokine in psoriatic inflammation. It has demonstrated efficacy in reducing joint symptoms and inhibiting radiographic progression. Etanercept targets TNF, ustekinumab targets IL-12/23, and rituximab targets CD20 on B cells. NCBI
Which composite index is specifically designed to assess overall disease activity in psoriatic arthritis?
Psoriatic Arthritis Disease Activity Score (PASDAS)
Simplified Disease Activity Index (SDAI)
Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)
Disease Activity Score-28 (DAS28)
PASDAS is a validated composite measure that includes joints, enthesitis, dactylitis, patient global assessment, and inflammatory markers, tailored for psoriatic arthritis. DAS28 and SDAI are designed for rheumatoid arthritis, and BASDAI for ankylosing spondylitis. NCBI
Apremilast, an oral therapy for psoriatic arthritis, exerts its effect by inhibiting which intracellular enzyme?
Cyclooxygenase-2 (COX-2)
Phosphodiesterase 5 (PDE5)
Phosphodiesterase 4 (PDE4)
5-Lipoxygenase (5-LOX)
Apremilast specifically inhibits PDE4, leading to increased intracellular cyclic AMP and modulation of pro- and anti-inflammatory mediators in psoriatic arthritis. This mechanism reduces TNF-?, IL-17, and IL-23 production. It is the first oral PDE4 inhibitor approved for this condition. American College of Rheumatology
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Study Outcomes

  1. Understand Core Symptoms -

    Recognize key psoriatic arthritis symptoms such as joint pain, stiffness, and skin changes to improve early detection.

  2. Identify Underlying Causes -

    Explain the genetic, immune, and environmental factors that contribute to the development of psoriatic arthritis.

  3. Differentiate Psoriatic Arthritis from Other Conditions -

    Compare and contrast psoriatic arthritis symptoms with those of rheumatoid arthritis and osteoarthritis for accurate assessment.

  4. Analyze Treatment and Care Strategies -

    Examine common medical and lifestyle interventions to manage psoriatic arthritis effectively.

  5. Apply Knowledge in the Psoriatic Arthritis Quiz -

    Use what you've learned to answer targeted psoriatic arthritis questions and validate your understanding.

  6. Evaluate Personal or Caregiving Approaches -

    Assess how to adapt insights to patient care or self-management for better quality of life.

Cheat Sheet

  1. Symptom Spectrum and Mnemonic "PAINS" -

    Psoriatic arthritis often presents with Pain, Asymmetry, Inflammation, Nail changes, and Spondylitis - remembered by the "PAINS" mnemonic to sharpen your recall for any psoriatic arthritis symptoms quiz. Recognizing dactylitis ("sausage digits") and enthesitis boosts your confidence when you test your psoriatic arthritis knowledge. The American College of Rheumatology lists nail pitting and DIP joint involvement as hallmark features.

  2. Immunogenetics and Risk Factors -

    Research shows a strong association with HLA-B27 and family history, so remembering "27" can help in psoriatic arthritis trivia rounds. Environmental triggers like infections and trauma can precipitate flares by activating T-cells and cytokines (TNF-α, IL-17). A 2020 article in Arthritis & Rheumatology underscores the role of gut microbiome imbalances in susceptibility.

  3. CASPAR Diagnostic Criteria Simplified -

    The CASPAR (ClASsification of Psoriatic ARthritis) criteria require inflammatory articular disease plus ≥3 points from psoriasis, nail dystrophy, negative rheumatoid factor, dactylitis, or juxta-articular new bone formation. Committing this formula to memory will help you ace psoriatic arthritis questions in any quiz. Validation studies in journals like Annals of the Rheumatic Diseases report >90% specificity.

  4. Pharmacologic Treatment Milestones -

    First-line NSAIDs ease pain, while conventional DMARDs (methotrexate, sulfasalazine) and biologics (TNF inhibitors, IL-17 blockers) form a step-up strategy - you can remember "NDB" (NSAIDs-DMARDs-Biologics) for easy recall during your psoriatic arthritis quiz. Landmark trials in The New England Journal of Medicine show TNF inhibitors significantly slow radiographic progression. Always link mechanism of action to drug class to reinforce retention.

  5. Monitoring and "Treat-to-Target" Approach -

    Regular assessment of joint counts, CRP/ESR levels, and imaging aligns with a treat-to-target strategy aimed at minimal disease activity - key content for any psoriatic arthritis trivia or quiz. The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) recommends adjusting therapy every 3 - 6 months if targets aren't met. Using a chart to track scores helps you test your psoriatic arthritis knowledge under real-world conditions.

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