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Test Your Human Stomach Knowledge Now!

Ready for our stomach anatomy quiz? Let's begin!

Difficulty: Moderate
2-5mins
Learning OutcomesCheat Sheet
Paper art illustration of human stomach cross section showing inner layers and tissues on teal background for anatomy quiz

Think you know your gut? Take our Quick Stomach Quiz: Test Your Anatomy Knowledge and challenge your mastery of the digestive world! This free stomach quiz asks about acid balance, enzyme action, and muscle roles in digestion. Whether you want to gauge your skills in a human stomach anatomy quiz or tackle a fun stomach function quiz, you'll sharpen your understanding and enjoy digestive system trivia. Curious about related areas? Try the abdominal anatomy quiz or explore our gastrointestinal anatomy quiz . Ready to boost your stomach health quiz score? Click Start now and let's get quizzing!

What is the primary digestive function of the stomach?
Protein digestion
Fat absorption
Carbohydrate absorption
Vitamin synthesis
The stomach secretes hydrochloric acid and pepsin to begin the breakdown of proteins into peptides. It does not significantly absorb carbohydrates, fats, or vitamins; those functions occur mainly in the small intestine. Source
Which type of muscle tissue composes the wall of the stomach?
Smooth muscle
Striated muscle
Skeletal muscle
Cardiac muscle
The stomach wall is made of smooth muscle, which operates involuntarily to mix and propel food. Skeletal and cardiac muscles are found in voluntary and heart tissues, respectively. Source
What is the name of the region of the stomach closest to the esophagus?
Fundus
Pylorus
Cardia
Body
The cardia is the region where the esophagus enters the stomach. The fundus sits above the cardia, the body is the main central region, and the pylorus is the distal part leading to the duodenum. Source
Which structure controls the exit of chyme from the stomach into the duodenum?
Lower esophageal sphincter
Ileocecal valve
Pyloric sphincter
Cardiac sphincter
The pyloric sphincter is a muscular ring that regulates the passage of partly digested food from the stomach to the duodenum. The cardiac sphincter is at the stomach entrance, and the ileocecal valve is between small and large intestines. Source
What are the folds in the gastric mucosa called?
Plicae circulares
Rugae
Crypts
Villi
Rugae are the folds in the stomach lining that allow it to expand when food enters. Villi are in the small intestine, plicae circulares are circular folds there, and crypts refer to intestinal glands. Source
Which acid is secreted by parietal cells in the stomach?
Sulfuric acid
Lactic acid
Acetic acid
Hydrochloric acid
Parietal cells in the stomach secrete hydrochloric acid (HCl), which lowers the pH and activates pepsinogen to pepsin. Other acids are not produced by gastric mucosa. Source
What is the approximate pH range of gastric juice?
6.5 to 8.5
4.5 to 6.5
7.0 to 9.0
1.5 to 3.5
Gastric juice is highly acidic, typically ranging from pH 1.5 to 3.5, to facilitate protein digestion and kill pathogens. Higher pH values are found in other parts of the digestive tract. Source
In which abdominal quadrant is the stomach primarily located?
Left lower quadrant
Left upper quadrant
Right lower quadrant
Right upper quadrant
The stomach lies predominantly in the left upper quadrant of the abdomen, under the left costal margin. The right upper quadrant contains liver and gallbladder. Source
Which cells in the stomach secrete hydrochloric acid?
Chief cells
Parietal cells
G cells
Mucous cells
Parietal cells, located in the gastric glands of the fundus and body, secrete hydrochloric acid. G cells release gastrin, chief cells release pepsinogen, and mucous cells secrete protective mucus. Source
Which layer of the stomach lies directly beneath the mucosa?
Submucosa
Adventitia
Serosa
Muscularis externa
The submucosa is a connective tissue layer beneath the mucosa that contains blood vessels and nerves. The muscularis externa and serosa are more external layers. Source
Which hormone primarily stimulates gastric acid secretion?
Motilin
Secretin
Cholecystokinin
Gastrin
Gastrin is secreted by G cells in the stomach and increases acid secretion from parietal cells. Secretin and CCK act mainly on the pancreas and gallbladder. Source
Which nerve is responsible for parasympathetic innervation of the stomach?
Splanchnic nerves
Phrenic nerve
Hypoglossal nerve
Vagus nerve
The vagus nerve provides parasympathetic fibers to the stomach, promoting acid secretion and motility. The phrenic nerve supplies the diaphragm, and splanchnic nerves are sympathetic. Source
Which nutrient content most strongly delays gastric emptying?
Fat-rich meals
Electrolyte solutions
High-protein meals
High carbohydrate meals
High-fat meals slow gastric emptying by stimulating release of hormones like CCK that delay gastric motility. Carbohydrates and proteins empty more quickly. Source
What is the name of the first part of the small intestine that receives chyme from the stomach?
Cecum
Ileum
Duodenum
Jejunum
The duodenum is the proximal portion of the small intestine that connects to the pylorus of the stomach. Jejunum and ileum follow, and the cecum is part of the large intestine. Source
Gastric pits are the openings to which structures?
Muscular layers
Gastric glands
Lymphatic ducts
Submucosal vessels
Gastric pits are indentations in the mucosa that lead to the gastric glands, where acid and enzymes are secreted. Muscular layers and vessels lie deeper. Source
What is the role of intrinsic factor produced in the stomach?
Stimulates pepsinogen secretion
Facilitates vitamin B12 absorption
Enhances calcium absorption
Neutralizes gastric acid
Intrinsic factor, secreted by parietal cells, binds vitamin B12 and enables its absorption in the ileum. Without it, pernicious anemia develops. Source
Which artery is the main blood supply to the lesser curvature of the stomach?
Short gastric arteries
Right gastric artery
Left gastric artery
Left gastroepiploic artery
The left gastric artery, a branch of the celiac trunk, supplies the upper lesser curvature. The right gastric artery supplies the lower lesser curvature. Source
Where do lymphatic vessels from the stomach primarily drain?
Axillary lymph nodes
Inguinal lymph nodes
Mesenteric lymph nodes
Celiac lymph nodes
Lymph from the stomach drains into the celiac lymph nodes near the celiac trunk. Mesenteric nodes serve the intestines, and inguinal/axillary nodes serve limbs. Source
Which cells secrete pepsinogen in the gastric mucosa?
D cells
G cells
Parietal cells
Chief cells
Chief cells produce pepsinogen, which is converted to pepsin in acidic conditions. Parietal cells make acid, G cells secrete gastrin, and D cells secrete somatostatin. Source
What is the unique third layer of muscle in the stomach not found in most of the GI tract?
Longitudinal muscle layer
Oblique muscle layer
Circular muscle layer
Transverse muscle layer
The stomach's muscularis has an additional oblique layer beneath the circular and longitudinal layers, aiding in churning food. Other GI segments have only two muscle layers. Source
Vagal stimulation has which effect on the pyloric sphincter?
Contraction
Spasm
No effect
Relaxation
Parasympathetic (vagal) input relaxes the pyloric sphincter to promote gastric emptying. Sympathetic activation would constrict it. Source
In which region of the stomach is acid production highest?
Cardia
Pylorus
Fundus
Antrum
The fundus contains the greatest density of parietal cells, making it the primary site of acid secretion. The antrum and pylorus have fewer acid-producing cells. Source
What is the role of somatostatin in the regulation of gastric secretion?
Enhances motility
Inhibits gastrin release and acid secretion
Stimulates pepsinogen release
Promotes mucus production
Somatostatin, secreted by D cells in the stomach, inhibits G-cell release of gastrin and directly suppresses parietal cell acid secretion. It acts as a key negative regulator. Source
Zollinger-Ellison syndrome is characterized by which of the following?
Gastrin-secreting tumor causing excess acid
Excess somatostatin secretion
Helicobacter pylori infection
Autoimmune destruction of parietal cells
Zollinger-Ellison syndrome involves a gastrin-secreting (gastrinoma) tumor, usually in the pancreas or duodenum, resulting in acid hypersecretion and peptic ulcers. Source
Where do the gastric slow waves (basic electrical rhythm) originate in the stomach?
Pyloric sphincter
Lesser curvature of the fundus
Greater curvature of the corpus
Antrum
Gastric slow waves originate from pacemaker cells along the greater curvature in the corpus and set the pace of muscular contractions. The antrum propagates these waves distally. Source
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Study Outcomes

  1. Identify Stomach Regions -

    After completing this stomach quiz, you will be able to pinpoint and name the major anatomical sections of the human stomach, including the fundus, body, and pylorus.

  2. Explain Gastric Functions -

    You will understand how mechanical churning and chemical digestion occur within the stomach and describe the roles of acid and enzymes in breaking down food.

  3. Analyze Digestive Processes -

    Engaging with our human stomach anatomy quiz will help you trace the movement of food through the digestive tract and evaluate the stomach's contribution to nutrient absorption.

  4. Assess Stomach Health -

    You will learn to recognize common signs of healthy versus impaired stomach function and understand factors that influence gastric health.

  5. Apply Knowledge to Trivia -

    By taking this digestive system trivia challenge, you will be prepared to answer related questions confidently and reinforce your mastery of stomach anatomy.

Cheat Sheet

  1. Gastric Regions and Landmarks -

    The stomach is divided into four regions: cardia, fundus, body, and pylorus. Use the mnemonic "CFBP: Cows Find Best Pastures" to recall the sequence from the esophagus to the duodenum, a staple for any human stomach anatomy quiz. Recognizing these landmarks helps with digestive system trivia that focuses on region-specific functions.

  2. Gastric Secretions and pH Balance -

    Parietal cells produce hydrochloric acid (HCl) to maintain a gastric pH of 1.5 - 3.5, activating pepsinogen into pepsin - remember the reaction: pepsinogen + H+ → pepsin. Chief cells secrete pepsinogen, which is converted at low pH to digest proteins; this concept is often tested in a stomach function quiz. Disruptions in pH balance can lead to ulcers, a key topic in stomach health quizzes.

  3. Stomach Wall Layers -

    The stomach wall comprises four layers: mucosa, submucosa, muscularis externa, and serosa, often remembered by "My Smart Mother Sews." Each layer contributes to protection, secretion, motility, or support, forming a foundation for digestive system trivia. Detailed knowledge of these layers is crucial for acing a human stomach anatomy quiz.

  4. Sphincters and Food Transit -

    The lower esophageal sphincter (LES) prevents acid reflux, while the pyloric sphincter controls chyme release into the duodenum. Questions in a stomach quiz frequently ask about their roles, so recall that LES failure leads to GERD and pyloric dysfunction affects gastric emptying rate. Mastering these control points is essential for both anatomy and stomach function quizzes.

  5. Mechanical Mixing and Intrinsic Factor -

    Together, stomach peristalsis and rugae folds churn food into chyme, a concept often featured in digestive system trivia. Parietal cells also secrete intrinsic factor, crucial for vitamin B12 absorption in the ileum, an important stomach health quiz fact. Understanding both mechanical and secretory roles of the stomach ensures high scores on comprehensive stomach quizzes.

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