Put Your Glycolysis & Krebs Cycle Knowledge to the Test!
Think you can ace this glycolysis game? Take on the citric acid cycle challenge!
This quiz helps you review glycolysis and the Krebs (citric acid) cycle step by step and spot weak areas fast. Answer quick questions on key enzymes, inputs, outputs, and checkpoints, and see your score as you go so you can study smarter before an exam. Want a quick primer first? Try the glycolysis warm‑up .
Study Outcomes
- Calculate ATP Yield -
Determine the number of ATP molecules produced at key steps of glycolysis and the citric acid cycle using our interactive quiz format.
- Identify Key Enzymes -
Recognize and recall the main enzymes that catalyze each reaction in the glycolysis game and Krebs cycle quiz.
- Differentiate Critical Intermediates -
Distinguish important metabolites, such as fructose-1,6-bisphosphate and citrate, within the pathways of our TCA cycle game.
- Analyze Regulatory Points -
Evaluate major control sites and allosteric regulators that govern metabolic flux during the quiz challenges.
- Apply Mechanistic Knowledge -
Use your understanding of enzyme functions and reaction steps to solve citric acid cycle practice problems accurately.
- Assess Pathway Integration -
Connect how glycolysis and the Krebs cycle interlink to overall cellular energy production in our metabolism mastery quiz.
Cheat Sheet
- Glycolysis Overall Reaction & Net ATP Yield -
Glycolysis converts one glucose molecule into two pyruvates with a net gain of 2 ATP and 2 NADH per glucose (Lehninger Principles of Biochemistry, 7th ed.). Remember the overall equation: C₆H₂O₆ + 2 NAD❺ + 2 ADP + 2 Pi → 2 CH₃COCOO❻ + 2 NADH + 2 H❺ + 2 ATP + 2 H₂O. This foundation is critical for any krebs cycle quiz or glycolysis game challenge.
- Key Regulatory Enzymes in Glycolysis -
Three enzymes - hexokinase, phosphofructokinase-1 (PFK-1), and pyruvate kinase - act as major control points (Harvard Biochemistry Department). PFK-1, the rate-limiting step, is allosterically activated by AMP and inhibited by ATP and citrate. Understanding these controls is essential when playing a citric acid cycle game or tca cycle game to anticipate metabolic shifts.
- Mnemonic for Glycolytic Intermediates -
Use "Goodness Gracious, Father Franklin Did Go By Picking Pumpkins (to) Prepare Pies" to recall Glucose, Glucose-6-phosphate, Fructose-6-phosphate, Fructose-1,6-bisphosphate, DHAP, G3P, 1,3-Bisphosphoglycerate, 3PG, 2PG, PEP, Pyruvate (University of Cambridge Biochemistry Dept.). This vivid phrase helps cement the 10-step pathway in memory for any glycolysis and krebs quiz. Pair it with flashcards showing structures to boost retention.
- TCA Cycle Energy Yield per Acetyl-CoA -
Each acetyl-CoA entering the Krebs cycle produces 3 NADH, 1 FADH₂, and 1 GTP (or ATP) through eight enzymatic steps (Voet & Voet, Biochemistry, 4th ed.). This translates roughly to 10 ATP equivalents after oxidative phosphorylation. Mastering these yields will give you an edge in any krebs cycle quiz or citric acid cycle game.
- Link Reaction & Pyruvate Dehydrogenase Complex -
The pyruvate dehydrogenase complex (PDC) bridges glycolysis and the TCA cycle, converting pyruvate into acetyl-CoA while requiring five cofactors: TPP, lipoate, CoA, FAD, and NAD❺ (National Institutes of Health). PDC is tightly regulated by phosphorylation (inhibitory) and dephosphorylation (activating) mechanisms. Grasping this control is key for any tca cycle game or krebs cycle quiz scenario.
