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Take the ED Seizure Management Knowledge Test

Test Your Emergency Seizure Response Knowledge Today

Difficulty: Moderate
Questions: 20
Learning OutcomesStudy Material
Colorful paper art depicting a quiz on ED Seizure Management Knowledge Test

Ready to sharpen your emergency seizure protocols and ED seizure management skills? The ED Seizure Management Knowledge Test features 15 multiple-choice questions designed to challenge and refine your clinical decision-making. Ideal for emergency clinicians, nurses, and medical students seeking to assess their readiness in acute seizure care. Feel free to adapt any question in our editor to create personalized quizzes or explore related assessments like the Hospital ED Protocol Quiz and Search and Seizure Law Enforcement Quiz. Take this quiz now to validate your expertise and ensure the best patient outcomes.

What is the term for a seizure that lasts longer than 5 minutes or involves multiple seizures without return to baseline consciousness?
Status epilepticus
Tonic-clonic seizure
Atonic seizure
Absence seizure
Status epilepticus is defined as a single seizure lasting more than 5 minutes or recurrent seizures without recovery of consciousness between them. This classification prompts immediate aggressive management to prevent neuronal injury.
Which of the following is considered a generalized seizure?
Simple partial seizure
Focal aware seizure
Focal impaired awareness seizure
Tonic-clonic seizure
A tonic-clonic seizure is a primary generalized seizure that involves both hemispheres of the brain from onset. Focal aware and focal impaired awareness seizures originate in a localized area.
What is the first step in the initial management of a patient actively seizing in the emergency department?
Obtain an immediate EEG
Administer IV phenytoin
Obtain a head CT scan
Ensure airway patency and adequate breathing
The ABCs (airway, breathing, circulation) are the top priority in any seizing patient to prevent hypoxia and aspiration. Imaging and medications follow stabilization of vital functions.
Which benzodiazepine is considered first-line for acute seizure control in the ED?
Intravenous phenytoin
Intranasal midazolam
Intravenous lorazepam
Rectal diazepam
Intravenous lorazepam is preferred due to its rapid onset and intermediate duration of action. Rectal diazepam and intranasal midazolam are alternatives if IV access is unavailable, while phenytoin is a second-line agent.
For a patient with a first-time seizure in the ED, which imaging modality should be obtained emergently?
Brain MRI
Skull X-ray
Noncontrast head CT
PET scan
A noncontrast CT scan is indicated emergently to rule out hemorrhage or mass effect in new-onset seizures. MRI provides greater detail but is less accessible in the acute setting.
A patient exhibits rhythmic jerking movements confined to the right arm without loss of consciousness. What type of seizure is this?
Secondary generalized seizure
Generalized tonic-clonic seizure
Absence seizure
Focal aware seizure
A focal aware seizure (simple partial seizure) involves motor activity confined to a specific region, such as the right arm, without impairment of consciousness. Generalized seizures involve both hemispheres from onset.
After administering a benzodiazepine for status epilepticus without cessation of seizures, what is the recommended second-line agent?
Intravenous ketamine
Intravenous midazolam infusion
Intravenous fosphenytoin
Intravenous valproic acid
Intravenous fosphenytoin is a recommended second-line agent after benzodiazepines in status epilepticus per evidence-based protocols. Valproic acid is an alternative but not the primary second-line in many guidelines.
Which electrolyte abnormality is most likely to provoke an acute symptomatic seizure?
Hyponatremia
Hyperglycemia
Hypercalcemia
Metabolic alkalosis
Acute hyponatremia lowers neuronal threshold and can directly provoke seizures. Other electrolyte disturbances can have neurological effects but are less acutely epileptogenic.
Continuous EEG monitoring in the ED is most useful for detecting which condition?
Hypotension
Hyperglycemia
Hypoventilation
Nonconvulsive status epilepticus
Continuous EEG allows detection of nonconvulsive status epilepticus or subclinical seizures that are not evident on clinical exam. It does not monitor vital signs directly.
A patient becomes somnolent with a respiratory rate of 8 breaths per minute after lorazepam administration. Which finding is most concerning?
Elevated heart rate
Reduced respiratory rate
Mild hypertension
Normal oxygen saturation
A depressed respiratory rate after benzodiazepine indicates potential respiratory depression and risk of hypoventilation. Monitoring airway and ventilation is critical in this context.
Which clinical feature favors syncope over a seizure?
Prolonged postictal confusion
Focal motor jerking
Tongue biting
Prodrome of lightheadedness
A prodrome of lightheadedness or visual changes is more consistent with syncope. Tongue biting, postictal confusion, and focal jerking favor a seizure etiology.
In refractory status epilepticus, after benzodiazepines and fosphenytoin, what is the next recommended pharmacologic step?
Oral valproate
Topiramate enteral
Levetiracetam bolus
Phenobarbital
Phenobarbital is a recommended third-line agent in refractory status epilepticus when benzodiazepines and phenytoin/fosphenytoin have failed. It enhances GABAergic inhibition further.
When administering phenytoin in the ED, which lab value is most important to monitor?
Serum potassium
Serum amylase
Serum phenytoin level
Serum lactate
Monitoring serum phenytoin levels helps ensure therapeutic dosing and avoids toxicity. Other labs are not directly relevant to phenytoin management.
A postictal patient remains confused and agitated. What is the most appropriate next step in management?
Start continuous EEG
Ensure airway patency and provide supportive care
Perform immediate lumbar puncture
Administer IV valproate
Postictal patients often require airway protection and supportive measures until they regain baseline mental status. Invasive diagnostics and additional AEDs are unnecessary without ongoing seizure activity.
What defines refractory status epilepticus?
Multiple seizures within 24 hours
Any status epilepticus episode lasting more than 30 minutes
Seizure activity persisting after adequate doses of two antiepileptic medications
Status epilepticus in patients with epilepsy history
Refractory status epilepticus is defined as ongoing seizures despite adequate administration of two appropriate antiepileptic drugs. This classification guides escalation to anesthetic agents.
In a pregnant patient presenting with status epilepticus, which medication is considered safest as first-line therapy?
Valproic acid
Phenobarbital
Phenytoin
Intravenous lorazepam
Lorazepam is considered safe and effective for acute seizure control in pregnancy. Valproic acid carries a high teratogenic risk, and other agents have less favorable safety profiles.
Which antiepileptic drug is preferred in patients with severe hepatic dysfunction?
Phenytoin
Levetiracetam
Carbamazepine
Valproate
Levetiracetam is predominantly renally excreted and has minimal hepatic metabolism, making it preferable in liver failure. Valproate, carbamazepine, and phenytoin rely on hepatic metabolism and are less safe in this setting.
Periodic lateralized epileptiform discharges (PLEDs) on EEG in the ED most strongly suggest which condition?
Generalized absence seizures
Hypoglycemia
Migraine aura
Focal status epilepticus
PLEDs are EEG patterns often associated with focal seizures or ongoing focal status epilepticus. They are not features of absence seizures or metabolic disturbances like hypoglycemia.
Which agent, acting on NMDA receptors, is used in refractory status epilepticus?
Phenobarbital
Ketamine
Midazolam
Propofol
Ketamine antagonizes NMDA receptors and can be effective in refractory status epilepticus. Midazolam and propofol act primarily on GABA receptors, and phenobarbital is a barbiturate.
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Learning Outcomes

  1. Identify common seizure presentations and differential diagnoses in the ED
  2. Demonstrate immediate stabilization techniques for acute seizure patients
  3. Apply evidence-based medication protocols for seizure control
  4. Evaluate patient history and risk factors to guide management decisions
  5. Analyse real-time monitoring data to adjust treatment plans
  6. Master post-seizure care and patient education steps

Cheat Sheet

  1. Recognize the various types of seizures - Seizures can be generalized, affecting both sides of the brain, or partial, originating in one specific region. Spotting these differences in the emergency department is key to choosing the right treatment path. Sharpen your observation skills and make a confident diagnosis every time. Best Practices for Seizure Management In the Emergency Department
  2. Be aware of common seizure mimics - Not everything that looks like a seizure is one! Conditions like syncope, psychogenic non-epileptic events, and movement disorders can throw you off. Learning their clues helps you avoid misdiagnosis and get patients the correct care. Best Practices for Seizure Management In the Emergency Department
  3. Learn the immediate stabilization steps - When a patient seizes, securing the airway, providing oxygen, and monitoring vital signs are your first moves. Quick action prevents hypoxia and other complications. Practicing these steps drills them into muscle memory so you can act swiftly. Status Epilepticus - StatPearls
  4. Understand first-line treatment for status epilepticus - Benzodiazepines like lorazepam or diazepam are your go-to medications to halt ongoing seizures. Administer them rapidly and titrate based on response. Mastering dosages and timing can be a real lifesaver. Management of Status Epilepticus | AAFP
  5. Familiarize yourself with second-line antiepileptic drugs - If benzodiazepines don't work, drugs such as fosphenytoin, levetiracetam, or valproate are next in line. Knowing each medication's dosing, side effects, and interactions keeps you on top of tricky cases. It's like having backup superheroes at the ready! 2024 ACEP Adult Patients Presenting to the Emergency Department with Seizures Guidelines Summary
  6. Evaluate patient history thoroughly - Dig into medication adherence, substance use, and recent illnesses to pinpoint seizure triggers. A detailed history can reveal patterns that guide both acute management and long-term control. Think of it as detective work that leads to better outcomes. Best Practices for Seizure Management In the Emergency Department
  7. Utilize real-time monitoring tools - Continuous EEG and other monitoring devices give you a live window into seizure activity. This data helps you adjust treatments on the fly and catch subclinical seizures. Embrace technology to stay one step ahead of the storm. Status Epilepticus - StatPearls
  8. Master post-seizure care steps - After a seizure, watch for recurrence, check for injuries, and offer supportive care like hydration and comfort measures. Ensuring a calm environment and clear communication reduces patient anxiety. Good post-care sets the stage for a smooth recovery. Best Practices for Seizure Management In the Emergency Department
  9. Educate patients and caregivers - Teach them how to stick to medication schedules, recognize warning signs, and know when to call for help. Clear instructions and handy seizure action plans empower families and improve safety. Turn complex medical jargon into simple, memorable tips. Best Practices for Seizure Management In the Emergency Department
  10. Stay updated on the latest evidence-based guidelines - Medicine evolves fast, and seizure management is no exception. Regularly review new protocols and research to keep your practice cutting-edge. A commitment to continuous learning means the best care for your patients. 2024 ACEP Adult Patients Presenting to the Emergency Department with Seizures Guidelines Summary
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