Question 123

You are seeing a 52 year old gentleman in clinic with acute unilateral anterior scleritis. On dilated fundus exam, you also note a posterior uveitis in both eyes. His visual acuity is down in both eyes. On history, he tells you that he has had recurrent nose bleeds recently and his internist is working him up for acute glomerulonephritis. You astutely make the unifying diagnosis. In addition to corticosteroids, what medication is most effective at inducing remission in this disease acutely?
Cyclophosphamide
Cyclosporine
Methotrexate
Azathiaprine
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