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Quizzes > Health & Medicine > Human Anatomy & Medicine

Oxygenation NCLEX Quiz: Challenge Your Knowledge!

Ready to tackle NCLEX questions for oxygenation? Test your fundamentals now!

Difficulty: Moderate
2-5mins
Learning OutcomesCheat Sheet
Paper art illustration for an Oxygenation NCLEX Questions Quiz on a golden yellow background.

Are you ready to boost your confidence and master oxygenation nclex questions? Our free Oxygenation NCLEX Questions Quiz is designed to help nursing students and new grads sharpen key respiratory concepts and deepen their understanding of nursing fundamentals oxygenation. In just minutes, you'll tackle targeted nclex questions for oxygenation that reinforce airway management, gas exchange, and critical assessment skills. Explore essential oxygen NCLEX questions alongside practical insights from oxygenation nursing fundamentals . Step up, take the quiz now, and track your progress toward exam success!

Which muscle is the primary muscle responsible for inspiration?
Diaphragm
Intercostal muscles
Sternocleidomastoid
Pectoralis major
The diaphragm is the main muscle of inspiration, contracting to increase thoracic volume and facilitate lung expansion. Intercostal muscles assist but are secondary in quiet breathing. Accessory muscles like the sternocleidomastoid engage during labored respiration. https://www.ncbi.nlm.nih.gov/books/NBK499877/
What parameter does pulse oximetry directly measure?
Arterial oxygen saturation (SpO2)
Partial pressure of oxygen (PaO2)
Hemoglobin concentration
End-tidal CO2
Pulse oximetry uses light absorption to noninvasively estimate the percentage of hemoglobin saturated with oxygen (SpO2). It does not directly measure PaO2, which requires arterial blood sampling. Hemoglobin concentration and end-tidal CO2 are assessed by other methods. https://www.ncbi.nlm.nih.gov/books/NBK482501/
Which patient position best promotes maximal lung expansion and oxygenation?
High Fowler’s position
Supine position
Trendelenburg position
Prone position
High Fowler’s position (sitting upright at 60–90°) allows gravity to lower the abdominal organs and gives the diaphragm more room to expand. This position enhances chest wall expansion and improves ventilation. Supine and Trendelenburg positions can restrict diaphragmatic movement. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631130/
Which clinical sign is often the earliest indicator of hypoxia?
Confusion or altered mental status
Cyanosis
Bradycardia
Hyperthermia
The brain is highly sensitive to low oxygen levels, so confusion or altered mental status often appears before visible signs like cyanosis. Cyanosis occurs when desaturation is significant and hemoglobin is deoxygenated. Heart rate changes may accompany hypoxia but are less specific early on. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991150/
An arterial blood gas shows a PaO2 of 60 mmHg. How is this categorized?
Mild hypoxemia
Normal oxygenation
Hyperoxemia
Severe hypoxemia
A PaO2 between 60 and 79 mmHg is classified as mild hypoxemia. Normal PaO2 ranges from 80 to 100 mmHg. Values below 60 mmHg indicate more severe hypoxemia requiring prompt intervention. https://www.ncbi.nlm.nih.gov/books/NBK537181/
Which intervention most effectively reduces the risk of postoperative atelectasis?
Early ambulation
Strict bed rest
Low-dose opioid administration
Trendelenburg positioning
Early ambulation encourages deep breathing and coughing, promoting full lung expansion and preventing alveolar collapse. Bed rest and inadequate pain control increase the risk for shallow breathing and atelectasis. Trendelenburg position can worsen respiratory mechanics postoperatively. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934665/
Positive end-expiratory pressure (PEEP) primarily helps by:
Increasing functional residual capacity
Decreasing venous return
Lowering cardiac output
Promoting pulmonary shunting
PEEP prevents alveolar collapse at end expiration, thereby increasing functional residual capacity (FRC) and improving oxygenation. While excessive PEEP can decrease venous return, its main benefit is keeping alveoli open. It reduces shunting by improving ventilation-perfusion matching. https://www.ncbi.nlm.nih.gov/books/NBK537170/
What is the recommended oxygen saturation target for most patients with COPD?
88%–92%
95%–100%
75%–80%
80%–85%
Patients with COPD often retain CO2 and depend on hypoxic drive; targeting 88%–92% balances oxygenation without suppressing respiratory drive. Excessive oxygenation can lead to CO2 retention and respiratory acidosis. Saturations above 95% are generally avoided in COPD exacerbations. https://goldcopd.org/
Interpret the following ABG: pH 7.30, PaCO2 50 mmHg, HCO3– 24 mEq/L.
Respiratory acidosis
Metabolic acidosis
Respiratory alkalosis
Metabolic alkalosis
A pH below 7.35 with an elevated PaCO2 indicates respiratory acidosis due to CO2 retention. The normal bicarbonate reflects a primary respiratory disorder without metabolic compensation. Metabolic acidosis would present with low HCO3–. https://www.ncbi.nlm.nih.gov/books/NBK482341/
Which breath sound is characterized by low-pitched, continuous snoring or gurgling sounds?
Rhonchi
Crackles
Wheezes
Stridor
Rhonchi are low-pitched, continuous sounds often resembling snoring, caused by air moving through secretions in larger airways. Crackles are discontinuous popping sounds in smaller airways. Wheezes are high-pitched musical sounds. https://www.ncbi.nlm.nih.gov/books/NBK536931/
When teaching incentive spirometry, the nurse should instruct the patient to:
Inhale slowly and deeply to reach the target volume
Exhale forcefully into the device
Hold their breath for 15 seconds after exhalation
Use it only once per day
Incentive spirometry works by encouraging slow, deep inhalation to maximize alveolar inflation and prevent atelectasis. Exhaling forcefully is not part of proper use. Breath holding occurs at peak inspiration for brief alveolar expansion. It should be used multiple times daily. https://www.ncbi.nlm.nih.gov/books/NBK482433/
Administration of a bronchodilator like albuterol primarily results in:
Relaxation of bronchial smooth muscle
Increased mucus production
Vasoconstriction of pulmonary vessels
Thickening of airway secretions
Albuterol is a ?2-agonist that relaxes bronchial smooth muscle, reducing airway resistance and improving airflow. It does not increase mucus production or thicken secretions. Vasoconstriction of pulmonary vessels is not its mechanism. https://www.ncbi.nlm.nih.gov/books/NBK482329/
Which condition primarily increases physiologic dead space, leading to ventilation without perfusion?
Pulmonary embolism
Pulmonary edema
Asthma exacerbation
Pneumonia
A pulmonary embolism blocks pulmonary blood flow to ventilated alveoli, creating dead space where ventilation occurs without perfusion. Pulmonary edema and pneumonia impair gas exchange but do not primarily cause dead space. Asthma limits airflow but usually preserves perfusion. https://www.ncbi.nlm.nih.gov/books/NBK537302/
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Study Outcomes

  1. Understand Oxygenation Physiology -

    Explain the key components of oxygen transport and exchange in the body, including gas diffusion and hemoglobin saturation mechanisms.

  2. Interpret Oxygenation NCLEX Question Scenarios -

    Analyze clinical vignettes to identify signs of impaired oxygenation and prioritize appropriate nursing responses.

  3. Apply Oxygen Delivery Methods -

    Select and justify the use of various oxygen delivery devices, such as nasal cannulas and masks, based on patient assessment.

  4. Differentiate Types of Hypoxia -

    Distinguish among hypoxic, anemic, circulatory, and histotoxic hypoxia and their implications for nursing care.

  5. Implement Nursing Interventions for Oxygenation -

    Outline evidence-based strategies, including positioning and airway clearance techniques, to enhance patient oxygenation.

  6. Evaluate Patient Oxygenation Status -

    Assess and interpret oxygenation parameters such as SpO2, arterial blood gas values, and respiratory rate to guide care decisions.

Cheat Sheet

  1. Respiratory Physiology & Gas Exchange -

    Review alveolar ventilation and perfusion using the V/Q ratio (ventilation/perfusion) to understand how oxygen moves into the blood. Remember that a normal V/Q of 0.8 ensures efficient gas exchange - this concept is frequently tested in oxygenation NCLEX questions (Guyton & Hall Physiology).

  2. Arterial Blood Gas Interpretation -

    Master the ROME mnemonic (Respiratory Opposite, Metabolic Equal) to quickly categorize ABG imbalances: pH and PaCO₂ move opposite in respiratory issues, and pH and HCO₃❻ move together in metabolic issues. Practicing with sample ABG values solidifies your skills for nclex questions for oxygenation (American Thoracic Society).

  3. Oxygen Delivery Systems & Flow Rates -

    Memorize flow-rate ranges: nasal cannula (1 - 6 L/min), simple mask (5 - 8 L/min), and Venturi mask (24 - 50%). Understanding which device meets specific FiOâ‚‚ needs is a key component of oxygenation nursing fundamentals and often appears in oxygen nclex questions (AARC Guidelines).

  4. Recognizing Hypoxemia & Early Interventions -

    Identify signs such as tachypnea, restlessness, and SpOâ‚‚ below 90%, then implement priority interventions: raise the head of bed, administer prescribed oxygen, and recheck ABGs or pulse oximetry. Quick recognition and response bolster your confidence in nursing fundamentals oxygenation scenarios (AACN Practice Alerts).

  5. Chest Physiotherapy & Positioning -

    Employ techniques like percussion, vibration, and postural drainage to mobilize secretions; use "Good Lung Down" positioning when unilateral lung disease is present to maximize perfusion. These nursing fundamentals oxygenation strategies enhance lung expansion and are commonly featured in oxygenation NCLEX questions (CDC Respiratory Hygiene).

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