Seven questions on normal wound healing

Normal wound healing
Created 2020.
This exercise will ask you a set of seven questions on normal wound healing. Each question contains only one correct answer.
 
If you want to read up on it, you can do so by clicking on the link below.
 
 
Learning objectives
  • Describe epidermal and dermal wound repair
  • Name cells and cytokines involved in wound healing
Created by: Dr Muhammad Wasay Ali Khan, DermNet NZ Volunteer
Editor
: Adjunct A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand
Normal wound healing
Created 2020.
This exercise will ask you a set of seven questions on normal wound healing. Each question contains only one correct answer.
 
If you want to read up on it, you can do so by clicking on the link below.
 
 
Learning objectives
  • Describe epidermal and dermal wound repair
  • Name cells and cytokines involved in wound healing
Created by: Dr Muhammad Wasay Ali Khan, DermNet NZ Volunteer
Editor
: Adjunct A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand
1. In normal wound healing:
a. Haemostasis creates a protective wound scab allowing cell migration underneath
b. Full thickness wounds can regenerate much more rapidly than partial thickness wounds of the same surface area
c. Adult partial thickness wounds heal by regeneration with fibrosis
d. Fetal full thickness wounds heal by regeneration with fibrosis
2. Select the type of wound shown in the image above:
a. Acute surgical wound
b. Healing arterial ulcer
c. Healing venous ulcer
d. Chronic pressure ulcer
3. During epidermal repair of an acute wound:
a. Restoration of basement membrane occurs more quickly over granulation tissue than over uninjured dermis
b. Fibrin and platelets are deposited on the wound surface
c. Keratinocytes proliferate and migrate from the base of the wound
d. Collagen binds keratinocytes
4. In scar formation:
a. Hair follicles, sweat glands and melanocytes may not be replaced so the scar has a smooth uniform surface
b. As vascularisation decreases, the colour of the wound intensifies
c. Collagenase degrades the collagen and fibroblasts and reduces strength of the scar
d. Myofibroblasts create the parallel collagen bundles that form a scar
5. Moist wound healing:
a. Reduces activity of lytic enzymes
b. Reduces the cellular phase of matrix deposition
c. Prevent further tissue loss by desiccation
d. Facilitates fibroblast migration
6. During acute wound healing, dermal fibroblasts:
a. Proliferate because of interferon-β and interferon-γ
b. Prevent formation of hyaluronic acid and proteoglycans
c. Produce collagen matrix
d. Proliferate with macrophages, smooth muscle and endothelial cells to form granulation tissue
7. During dermal repair of an acute wound:
a. Release of C2 and C4 result in vasodilatation and inflammation
b. Chemotactic factors are released from platelets and injured tissues to attract neutrophils and monocytes
c. Interleukin-1 is released by platelets
d. Fibroblast growth factor is released by platelets
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